Compounds
| ID | Spectrum Quality | Annotated Name |
|---|
COMPOUND NPA007518
PROPERTIES
| NPAID | NPA007518 |
|---|---|
| CLUSTER ID | 3349 |
| NODE ID | 2533 |
| NAME | Tetarimycin A |
| FORMULA | C21H16O6 |
| MOLECULAR WEIGHT (Da) | 364.3530 |
| ACCURATE MASS (Da) | 364.0947 |
| ORIGIN ORGANISM TYPE | Bacterium |
| ORIGIN GENUS | eDNA |
| ORIGIN SPECIES | sp. |
| InChIKey | XQMPGQHPYUKJDG-UHFFFAOYSA-N |
| InChI | InChI=1S/C21H16O6/c1-8-4-9(22)5-11-14(8)19(26)16-17(18(11)25)21(2,3)12-6-10(23)7-13(24)15(12)20(16)27/h4-7,22-24H,1-3H3 |
| SMILES | CC1=C2C(=CC(=C1)O)C(=O)C3=C(C2=O)C(=O)C4=C(C=C(C=C4C3(C)C)O)O |
ORIGINAL ISOLATION REFERENCE
| CITATION | Kallifidas, Dimitris; Kang, Hahk-Soo; Brady, Sean F. Tetarimycin A, an MRSA-active antibiotic identified through induced expression of environmental DNA gene clusters Journal of the American Chemical Society 2012 134 (48) 19552-19555. | ||
|---|---|---|---|
| DOI | 10.1021/ja3093828 | PMID | 23157252 |
SYNTHESES
| CITATION 1 | Huang JK; Yang Lauderdale TL; Lin CC; Shia KS Total Synthesis of Tetarimycin A, (±)-Naphthacemycin A Journal of Organic Chemistry 2018 83 (12) 6508-6523. DOI: 10.1021/acs.joc.8b00802 PMID: 29785848 | ||
|---|---|---|---|
| CITATION 2 | Huang JK; Yang Lauderdale TL; Shia KS Studies on Antibiotics Active against Resistant Bacteria. Total Synthesis of MRSA-Active Tetarimycin A and Its Analogues. Organic Letters 2015 17 (17) 4248-4251. DOI: 10.1021/acs.orglett.5b02039 PMID: 26273719 | ||
