Loading...

Loading...

Compounds

COMPOUND NPA031269

STRUCTURE
Image structure
EXPORT OPTIONS PNG JSON SDF
PROJECT MOLECULE TO GLOBAL VIEW See Global
EXTERNAL LINKS
unichem logo
PROPERTIES
NPAID NPA031269
CLUSTER ID 1675
NODE ID 1369
NAME 2-Hydroxycyslabdan A
FORMULA C25H41NO6S
MOLECULAR WEIGHT (Da) 483.6710
ACCURATE MASS (Da) 483.2655
ORIGIN ORGANISM TYPE Bacterium
ORIGIN GENUS Streptomyces
ORIGIN SPECIES avermitilis SUKA22 (heterologous expression)
InChIKey PTRRHQHGAOYEKT-KYXZTKSHSA-N
InChI InChI=1S/C25H41NO6S/c1-7-15(2)8-9-19-24(6)12-17(28)11-23(4,5)20(24)10-21(29)25(19,32)14-33-13-18(22(30)31)26-16(3)27/h7-8,17-21,28-29,32H,1,9-14H2,2-6H3,(H,26,27)(H,30,31)/b15-8+/t17-,18-,19+,20-,21-,24+,25+/m0/s1
SMILES C=C/C(C)=C/C[C@@H]1[C@@]2(C)C[C@@H](O)CC(C)(C)[C@@H]2C[C@H](O)[C@@]1(O)CSC[C@H](NC(C)=O)C(=O)O
ORIGINAL ISOLATION REFERENCE
CITATION Haruo Ikeda, Kazuo Shin-ya, Tohru Nagamitsu, Hiroshi Tomoda Biosynthesis of mercapturic acid derivative of the labdane-type diterpene, cyslabdan that potentiates imipenem activity against methicillin-resistant Staphylococcus aureus: cyslabdan is generated by mycothiol-mediated xenobiotic detoxification. Journal of Industrial Microbiology and Biotechnology 2016 43 (2-3) 325-342.
DOI 10.1007/s10295-015-1694-6 PMID 26507838
ORIGINAL ISOLATION TAXONOMY
RANK NAME DB LINK NCBI
Domain Bacteria LPSN 2
Phylum Actinobacteria LPSN 201174
Class Actinobacteria LPSN -
Order Streptomycetales LPSN 85011
Family Streptomycetaceae LPSN 2062
Genus Streptomyces LPSN 1883
CLASSYFIRE
Show Hide
NP CLASSIFIER
Show Hide