Compounds
| ID | Spectrum Quality | Annotated Name |
|---|
COMPOUND NPA021254
PROPERTIES
| NPAID | NPA021254 |
|---|---|
| CLUSTER ID | 24 |
| NODE ID | 23 |
| NAME | Kynapcin-12 |
| FORMULA | C22H18O8 |
| MOLECULAR WEIGHT (Da) | 410.3780 |
| ACCURATE MASS (Da) | 410.1002 |
| ORIGIN ORGANISM TYPE | Fungus |
| ORIGIN GENUS | Polyozellus |
| ORIGIN SPECIES | multiplex |
| InChIKey | WOUMFZZOFGTIFS-UHFFFAOYSA-N |
| InChI | InChI=1S/C22H18O8/c1-11(23)29-21-17(13-3-7-15(25)8-4-13)20(28)22(30-12(2)24)18(19(21)27)14-5-9-16(26)10-6-14/h3-10,25-28H,1-2H3 |
| SMILES | CC(=O)OC1=C(C(=C(C(=C1C2=CC=C(C=C2)O)O)OC(=O)C)C3=CC=C(C=C3)O)O |
ORIGINAL ISOLATION REFERENCE
| CITATION | Lee HJ; Rhee IK; Lee KB; Yoo ID; Song KS Kynapcin-12, a New p-Terphenyl Derivative from Polyozellus multiplex. Inhibits Prolyl Endopeptidase Journal of Antibiotics 2000 53 (7) 714-719. | ||
|---|---|---|---|
| DOI | 10.7164/antibiotics.53.714 | PMID | 10994814 |
SYNTHESES
| CITATION 1 | Takahashi S; Yoshida A; Uesugi S; Hongo Y; Kimura K; Matsuoka K; Koshino H Structural revision of kynapcin-12 by total synthesis, and inhibitory activities against prolyl oligopeptidase and cancer cells. Bioorganic and Medicinal Chemistry Letters 2014 24 (15) 3373-6. DOI: 10.1016/j.bmcl.2014.05.091 PMID: 24948566 | ||
|---|---|---|---|
