Compounds
| ID | Spectrum Quality | Annotated Name |
|---|
COMPOUND NPA021089
PROPERTIES
| NPAID | NPA021089 |
|---|---|
| CLUSTER ID | 1150 |
| NODE ID | 983 |
| NAME | CC-1065 |
| FORMULA | C37H33N7O8 |
| MOLECULAR WEIGHT (Da) | 703.7120 |
| ACCURATE MASS (Da) | 703.2391 |
| ORIGIN ORGANISM TYPE | Bacterium |
| ORIGIN GENUS | Streptomyces |
| ORIGIN SPECIES | zeelensis sp. n. |
| InChIKey | UOWVMDUEMSNCAV-UHFFFAOYSA-N |
| InChI | InChI=1S/C37H33N7O8/c1-14-12-39-27-22(45)10-23-37(24(14)27)11-15(37)13-44(23)35(49)21-9-18-16-4-6-42(28(16)30(46)32(51-2)25(18)41-21)34(48)20-8-19-17-5-7-43(36(38)50)29(17)31(47)33(52-3)26(19)40-20/h8-10,12,15,39-41,46-47H,4-7,11,13H2,1-3H3,(H2,38,50) |
| SMILES | CC1=CNC2=C1C34CC3CN(C4=CC2=O)C(=O)C5=CC6=C7CCN(C7=C(C(=C6N5)OC)O)C(=O)C8=CC9=C1CCN(C1=C(C(=C9N8)OC)O)C(=O)N |
ORIGINAL ISOLATION REFERENCE
| CITATION | Hanka LJ; Dietz A; Gerpheide SA; Kuentzel SL; Martin DG CC-1065 (NSC-298223), a new antitumor antibiotic. Production, in vitro biological activity, microbiological assays and taxonomy of the producing microorganism. Journal of Antibiotics 1978 31 (12) 1211-1217. | ||
|---|---|---|---|
| DOI | 10.7164/antibiotics.31.1211 | PMID | 104946 |
SYNTHESES
| CITATION 1 | Imaizumi T; Yamashita Y; Nakazawa Y; Okano K; Sakata J; Tokuyama H Total Synthesis of (+)-CC-1065 Utilizing Ring Expansion Reaction of Benzocyclobutenone Oxime Sulfonate. Organic Letters 2019 21 (16) 6185-6189. DOI: 10.1021/acs.orglett.9b01690 PMID: 31188001 | ||
|---|---|---|---|
