Compounds
| ID | Spectrum Quality | Annotated Name |
|---|
COMPOUND NPA020673
PROPERTIES
| NPAID | NPA020673 |
|---|---|
| CLUSTER ID | 1770 |
| NODE ID | 1435 |
| NAME | Synerazol |
| FORMULA | C22H23NO7 |
| MOLECULAR WEIGHT (Da) | 413.4260 |
| ACCURATE MASS (Da) | 413.1475 |
| ORIGIN ORGANISM TYPE | Fungus |
| ORIGIN GENUS | Aspergillus |
| ORIGIN SPECIES | fumigatus SANK 10588 |
| InChIKey | UCUHTBUWKCQZNJ-WZNGDJORSA-N |
| InChI | InChI=1S/C22H23NO7/c1-4-5-11-14-16(29-14)15-12(2)17(24)21(30-15)19(26)22(28-3,23-20(21)27)18(25)13-9-7-6-8-10-13/h5-11,14,16,19,26H,4H2,1-3H3,(H,23,27)/b11-5-/t14-,16+,19-,21-,22-/m1/s1 |
| SMILES | CC/C=C\[C@@H]1[C@H](O1)C2=C(C(=O)[C@@]3(O2)[C@H]([C@@](NC3=O)(C(=O)C4=CC=CC=C4)OC)O)C |
ORIGINAL ISOLATION REFERENCE
| CITATION | Ando O; Satake H; Nakajima M; Sato A; Nakamura T; Kinoshita T; Furuya K; Haneishi T SYNERAZOL, A NEW ANTIFUNGAL ANTIBIOTIC Journal of Antibiotics 1991 44 (4) 382-389. | ||
|---|---|---|---|
| DOI | 10.7164/antibiotics.44.382 | PMID | 2032946 |
SYNTHESES
| CITATION 1 | Hayashi Y; Shoji M; Mukaiyama T; Gotoh H; Yamaguchi S; Nakata M; Kakeya H; Osada H First asymmetric total synthesis of synerazol, an antifungal antibiotic, and determination of its absolute stereochemistry. Journal of Organic Chemistry 2005 70 (14) 5643-54. DOI: 10.1021/jo050664x PMID: 15989349 | ||
|---|---|---|---|
