Compounds
| ID | Spectrum Quality | Annotated Name |
|---|
COMPOUND NPA018076
PROPERTIES
| NPAID | NPA018076 |
|---|---|
| CLUSTER ID | 26 |
| NODE ID | 25 |
| NAME | WAP-8294A2 |
| FORMULA | C73H111N17O21 |
| MOLECULAR WEIGHT (Da) | 1562.7890 |
| ACCURATE MASS (Da) | 1561.8140 |
| ORIGIN ORGANISM TYPE | Bacterium |
| ORIGIN GENUS | Lysobacter |
| ORIGIN SPECIES | sp. |
| InChIKey | LEKBQPKGXGFBAN-UHFFFAOYSA-N |
| InChI | InChI=1S/C73H111N17O21/c1-38(2)17-14-20-43-32-56(94)80-53(37-92)69(106)88-59(61(98)62(77)99)71(108)87-52(36-91)63(100)79-35-57(95)89(7)54(30-41-18-10-9-11-19-41)70(107)86-49(29-39(3)4)66(103)81-46(23-15-27-74)64(101)82-47(25-26-58(96)97)65(102)85-51(33-55(76)93)68(105)84-50(31-42-34-78-45-22-13-12-21-44(42)45)67(104)83-48(24-16-28-75)72(109)90(8)60(40(5)6)73(110)111-43/h9-13,18-19,21-22,34,38-40,43,46-54,59-61,78,91-92,98H,14-17,20,23-33,35-37,74-75H2,1-8H3,(H2,76,93)(H2,77,99)(H,79,100)(H,80,94)(H,81,103)(H,82,101)(H,83,104)(H,84,105)(H,85,102)(H,86,107)(H,87,108)(H,88,106)(H,96,97) |
| SMILES | CC(C)CCCC1CC(=O)NC(C(=O)NC(C(=O)NC(C(=O)NCC(=O)N(C(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N(C(C(=O)O1)C(C)C)C)CCCN)CC2=CNC3=CC=CC=C32)CC(=O)N)CCC(=O)O)CCCN)CC(C)C)CC4=CC=CC=C4)C)CO)C(C(=O)N)O)CO |
ORIGINAL ISOLATION REFERENCE
| CITATION | Kato, Azusa; Nakaya, Seigo; Kokubo, Naomi; Aiba, Yuji; Ohashi, Yoshitami; Hirata, Haruhisa; Fujii, Kiyonaga; Harada, Ken-Ichi A new anti-MRSA antibiotic complex, WAP-8294A. I. Taxonomy, isolation and biological activities Journal of Antibiotics 1998 51 (10) 929-935. | ||
|---|---|---|---|
| DOI | 10.7164/antibiotics.51.929 | PMID | 9917006 |
SYNTHESES
| CITATION 1 | Itoh H; Tokumoto K; Kaji T; Paudel A; Panthee S; Hamamoto H; Sekimizu K; Inoue M Total Synthesis and Biological Mode of Action of WAP-8294A2: A Menaquinone-Targeting Antibiotic. Journal of Organic Chemistry 2018 83 (13) 6924-6935. DOI: 10.1021/acs.joc.7b02318 PMID: 29019678 | ||
|---|---|---|---|
