Compounds
| ID | Spectrum Quality | Annotated Name |
|---|
COMPOUND NPA017584
PROPERTIES
| NPAID | NPA017584 |
|---|---|
| CLUSTER ID | 950 |
| NODE ID | 818 |
| NAME | Salinamide A |
| FORMULA | C51H69N7O15 |
| MOLECULAR WEIGHT (Da) | 1020.1470 |
| ACCURATE MASS (Da) | 1019.4852 |
| ORIGIN ORGANISM TYPE | Bacterium |
| ORIGIN GENUS | Streptomyces |
| ORIGIN SPECIES | sp. |
| InChIKey | UIHLRTKYJPYYEU-OBBNVNRZSA-N |
| InChI | InChI=1S/C51H69N7O15/c1-10-27(4)39-46(65)57-42-33-16-18-34(19-17-33)73-31(8)51(25-71-51)21-20-37(60)52-23-38(61)70-24-35(50(69)72-30(7)41(48(67)54-39)56-44(63)28(5)43(62)26(2)3)53-47(66)40(29(6)59)55-45(64)36(58(9)49(42)68)22-32-14-12-11-13-15-32/h11-21,26-31,35-36,39-43,59,62H,10,22-25H2,1-9H3,(H,52,60)(H,53,66)(H,54,67)(H,55,64)(H,56,63)(H,57,65)/b21-20+/t27-,28+,29+,30+,31+,35-,36-,39+,40+,41-,42-,43+,51-/m1/s1 |
| SMILES | CC[C@@H](C)[C@H]1C(=O)N[C@@H]2C3=CC=C(C=C3)O[C@H]([C@]4(CO4)/C=C/C(=O)NCC(=O)OC[C@H](C(=O)O[C@H]([C@H](C(=O)N1)NC(=O)[C@@H](C)[C@H](C(C)C)O)C)NC(=O)[C@@H](NC(=O)[C@H](N(C2=O)C)CC5=CC=CC=C5)[C@H](C)O)C |
ORIGINAL ISOLATION REFERENCE
| CITATION | Trischman, Jacqueline A.; Tapiolas, Dianne M.; Jensen, Paul R.; Dwight, Ryan; Fenical, William; McKee, Tawnya C.; Ireland, Chris M.; Stout, Thomas J.; Clardy, Jon Salinamides A and B: anti-inflammatory depsipeptides from a marine streptomycete Journal of the American Chemical Society 1994 116 (2) 757-758. | ||
|---|---|---|---|
| DOI | 10.1021/ja00081a042 | PMID | - |
SYNTHESES
| CITATION 1 | Tan L; Ma D Total synthesis of salinamide A: a potent anti-inflammatory bicyclic depsipeptide. Angewandte Chemie International Edition 2008 47 (19) 3614-3617. DOI: 10.1002/anie.200800397 PMID: 18383490 | ||
|---|---|---|---|
