Compounds
| ID | Spectrum Quality | Annotated Name |
|---|
COMPOUND NPA011772
PROPERTIES
| NPAID | NPA011772 |
|---|---|
| CLUSTER ID | 948 |
| NODE ID | 816 |
| NAME | Topostatin |
| FORMULA | C36H58N4O11S |
| MOLECULAR WEIGHT (Da) | 754.9440 |
| ACCURATE MASS (Da) | 754.3823 |
| ORIGIN ORGANISM TYPE | Bacterium |
| ORIGIN GENUS | Thermomonospora |
| ORIGIN SPECIES | alba (No. 1520) |
| InChIKey | XLDIAUNLPWGNHO-XWZQQIMHSA-N |
| InChI | InChI=1S/C36H58N4O11S/c1-8-9-10-11-12-13-22(2)14-15-23(3)16-18-29(41)24(4)17-19-30-26(6)34(44)39-27(7)35(45)38-21-25(5)33(43)40-28(36(46)50-30)20-31(32(37)42)51-52(47,48)49/h15-16,18,22,24-26,28,30-31H,7-14,17,19-21H2,1-6H3,(H2,37,42)(H,38,45)(H,39,44)(H,40,43)(H,47,48,49)/b18-16+,23-15+ |
| SMILES | CCCCCCCC(C)C/C=C(\C)/C=C/C(=O)C(C)CCC1C(C(=O)NC(=C)C(=O)NCC(C(=O)NC(C(=O)O1)CC(C(=O)N)OS(=O)(=O)O)C)C |
ORIGINAL ISOLATION REFERENCE
| CITATION | Suzuki, Keitarou; Nagao, Kazuhiko; Monnai, Yutaka; Yagi, Akemi; Uyeda, Masaru Topostatin, a novel inhibitor of topoisomerases I and II produced by Thermomonospora alba strain No. 1520. I. Taxonomy, fermentation, isolation and biological activities Journal of Antibiotics 1998 51 (11) 991-998. | ||
|---|---|---|---|
| DOI | 10.7164/antibiotics.52.460 | PMID | 10480569 |
