Compounds
| ID | Spectrum Quality | Annotated Name |
|---|---|---|
| CCMSLIB00004695632 | Bronze | Aphidicolin |
| CCMSLIB00000081679 | Bronze | Aphidicolin |
| CCMSLIB00000081680 | Bronze | Aphidicolin |
| CCMSLIB00004695630 | Bronze | Aphidicolin |
| CCMSLIB00004695633 | Bronze | Aphidicolin |
| CCMSLIB00004695634 | Bronze | Aphidicolin |
| CCMSLIB00004695635 | Bronze | Aphidicolin |
| CCMSLIB00004695636 | Bronze | Aphidicolin |
| CCMSLIB00004695637 | Bronze | Aphidicolin |
| CCMSLIB00004695638 | Bronze | Aphidicolin |
| CCMSLIB00004695639 | Bronze | Aphidicolin |
| CCMSLIB00004695640 | Bronze | Aphidicolin |
| CCMSLIB00004695641 | Bronze | Aphidicolin |
| CCMSLIB00004695642 | Bronze | Aphidicolin |
| CCMSLIB00004695643 | Bronze | Aphidicolin |
| CCMSLIB00004695644 | Bronze | Aphidicolin |
| CCMSLIB00004695631 | Bronze | Aphidicolin |
| CCMSLIB00010114485 | Gold | 3 |
| CCMSLIB00010114486 | Gold | 3 |
| CCMSLIB00010114487 | Gold | 3 |
| CCMSLIB00010125815 | Gold | 3 |
| CCMSLIB00010125816 | Gold | 3 |
| CCMSLIB00010125817 | Gold | 3 |
COMPOUND NPA010945
PROPERTIES
| NPAID | NPA010945 |
|---|---|
| CLUSTER ID | 29 |
| NODE ID | 28 |
| NAME | Aphidicolin |
| FORMULA | C20H34O4 |
| MOLECULAR WEIGHT (Da) | 338.4880 |
| ACCURATE MASS (Da) | 338.2457 |
| ORIGIN ORGANISM TYPE | Fungus |
| ORIGIN GENUS | Cephalosporium |
| ORIGIN SPECIES | aphidicola |
| InChIKey | NOFOAYPPHIUXJR-APNQCZIXSA-N |
| InChI | InChI=1S/C20H34O4/c1-17(11-21)15-4-3-13-9-14-10-19(13,7-8-20(14,24)12-22)18(15,2)6-5-16(17)23/h13-16,21-24H,3-12H2,1-2H3/t13-,14+,15-,16+,17-,18-,19-,20-/m0/s1 |
| SMILES | C[C@]12CC[C@H]([C@@]([C@@H]1CC[C@@H]3[C@@]24CC[C@@]([C@H](C3)C4)(CO)O)(C)CO)O |
ORIGINAL ISOLATION REFERENCE
| CITATION | Dalziel, William; Hesp, Barrie; Stevenson, Karen M; Jarvis, John AJ The structure and absolute configuration of the antibiotic aphidicolin: a tetracyclic diterpenoid containing a new ring system Journal of the Chemical Society, Perkin Transactions 1 1973 2841-2851. | ||
|---|---|---|---|
| DOI | 10.1039/p19730002841 | PMID | - |
SYNTHESES
| CITATION 1 | Toyota M; Sasaki M; Ihara M Diastereoselective formal total synthesis of the DNA polymerase alpha inhibitor, aphidicolin, using palladium-catalyzed cycloalkenylation and intramolecular Diels-Alder reactions. Organic Letters 2003 5 (8) 1193-5. DOI: 10.1021/ol034027+ PMID: 12688717 | ||
|---|---|---|---|
