Compounds
ID | Spectrum Quality | Annotated Name |
---|
COMPOUND NPA007938
PROPERTIES
NPAID | NPA007938 |
---|---|
CLUSTER ID | 841 |
NODE ID | 730 |
NAME | Salinosporamide D |
FORMULA | C14H19NO4 |
MOLECULAR WEIGHT (Da) | 265.3090 |
ACCURATE MASS (Da) | 265.1314 |
ORIGIN ORGANISM TYPE | Bacterium |
ORIGIN GENUS | Salinispora |
ORIGIN SPECIES | tropica |
InChIKey | XSAPVTUEGDPTEC-BTXSVYSASA-N |
InChI | InChI=1S/C14H19NO4/c1-8-11(17)15-14(12(18)19-13(8,14)2)10(16)9-6-4-3-5-7-9/h4,6,8-10,16H,3,5,7H2,1-2H3,(H,15,17)/t8-,9+,10-,13-,14-/m0/s1 |
SMILES | C[C@H]1C(=O)N[C@@]2([C@]1(OC2=O)C)[C@H]([C@H]3CCCC=C3)O |
ORIGINAL ISOLATION REFERENCE
CITATION | Reed, Katherine A.; Manam, Rama Rao; Mitchell, Scott S.; Xu, Jianlin; Teisan, Sy; Chao, Ta-Hsiang; Deyanat-Yazdi, Gordafaried; Neuteboom, Saskia T. C.; Lam, Kin S.; Potts, Barbara C. M. Salinosporamides D-J from the marine actinomycete Salinispora tropica, bromosalinosporamide, and thioester derivatives are potent inhibitors of the 20S proteasome Journal of Natural Products 2007 70 (2) 269-276. | ||
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DOI | 10.1021/np0603471 | PMID | 17243724 |