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Compounds

COMPOUND NPA007938

STRUCTURE
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PROPERTIES
NPAID NPA007938
CLUSTER ID 841
NODE ID 730
NAME Salinosporamide D
FORMULA C14H19NO4
MOLECULAR WEIGHT (Da) 265.3090
ACCURATE MASS (Da) 265.1314
ORIGIN ORGANISM TYPE Bacterium
ORIGIN GENUS Salinispora
ORIGIN SPECIES tropica
InChIKey XSAPVTUEGDPTEC-BTXSVYSASA-N
InChI InChI=1S/C14H19NO4/c1-8-11(17)15-14(12(18)19-13(8,14)2)10(16)9-6-4-3-5-7-9/h4,6,8-10,16H,3,5,7H2,1-2H3,(H,15,17)/t8-,9+,10-,13-,14-/m0/s1
SMILES C[C@H]1C(=O)N[C@@]2([C@]1(OC2=O)C)[C@H]([C@H]3CCCC=C3)O
ORIGINAL ISOLATION REFERENCE
CITATION Reed, Katherine A.; Manam, Rama Rao; Mitchell, Scott S.; Xu, Jianlin; Teisan, Sy; Chao, Ta-Hsiang; Deyanat-Yazdi, Gordafaried; Neuteboom, Saskia T. C.; Lam, Kin S.; Potts, Barbara C. M. Salinosporamides D-J from the marine actinomycete Salinispora tropica, bromosalinosporamide, and thioester derivatives are potent inhibitors of the 20S proteasome Journal of Natural Products 2007 70 (2) 269-276.
DOI 10.1021/np0603471 PMID 17243724
ORIGINAL ISOLATION TAXONOMY
RANK NAME DB LINK NCBI
Domain Bacteria LPSN 2
Phylum Actinobacteria LPSN 201174
Class Actinobacteria LPSN -
Order Micromonosporales LPSN 85008
Family Micromonosporaceae LPSN 28056
Genus Salinispora LPSN 168694
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