Compounds
| ID | Spectrum Quality | Annotated Name |
|---|
COMPOUND NPA006168
PROPERTIES
| NPAID | NPA006168 |
|---|---|
| CLUSTER ID | 1542 |
| NODE ID | 1266 |
| NAME | Migrastatin |
| FORMULA | C27H39NO7 |
| MOLECULAR WEIGHT (Da) | 489.6090 |
| ACCURATE MASS (Da) | 489.2727 |
| ORIGIN ORGANISM TYPE | Bacterium |
| ORIGIN GENUS | Streptomyces |
| ORIGIN SPECIES | sp. MK929-43F1 |
| InChIKey | OGYMUMAKGYYNHV-DGAGQXFWSA-N |
| InChI | InChI=1S/C27H39NO7/c1-17-14-18(2)27(35-25(32)13-8-6-5-7-12-22(34-4)26(17)33)19(3)21(29)11-9-10-20-15-23(30)28-24(31)16-20/h7-8,12-14,17,19-20,22,26-27,33H,5-6,9-11,15-16H2,1-4H3,(H,28,30,31)/b12-7+,13-8+,18-14- |
| SMILES | CC1/C=C(\C(OC(=O)/C=C/CC/C=C/C(C1O)OC)C(C)C(=O)CCCC2CC(=O)NC(=O)C2)/C |
ORIGINAL ISOLATION REFERENCE
| CITATION | Nakae; Yoshimoto; Sawa; Homma; Hamada; Takeuchi; Imoto Migrastatin, a new inhibitor of tumor cell migration from Streptomyces sp. MK929-43F1 taxonomy, fermentation, isolation and biological activities Journal of Antibiotics 2000 53 (10) 1130-1136. | ||
|---|---|---|---|
| DOI | 10.7164/antibiotics.53.1130 | PMID | 11132958 |
SYNTHESES
| CITATION 1 | Gaul C; Njardarson JT; Danishefsky SJ The total synthesis of (+)-migrastatin. Journal of the American Chemical Society 2003 125 (20) 6042-6043. DOI: 10.1021/ja0349103 PMID: 12785819 | ||
|---|---|---|---|
