Compounds
| ID | Spectrum Quality | Annotated Name |
|---|
COMPOUND NPA005497
PROPERTIES
| NPAID | NPA005497 |
|---|---|
| CLUSTER ID | 2690 |
| NODE ID | 548 |
| NAME | Chlorotonil A |
| FORMULA | C26H32Cl2O4 |
| MOLECULAR WEIGHT (Da) | 479.4440 |
| ACCURATE MASS (Da) | 478.1678 |
| ORIGIN ORGANISM TYPE | Bacterium |
| ORIGIN GENUS | Sorangium |
| ORIGIN SPECIES | cellulosum |
| InChIKey | RQYZFUUTQJMTMJ-JCSZEPHKSA-N |
| InChI | InChI=1S/C26H32Cl2O4/c1-14-12-16(3)21-19(13-14)10-11-20-15(2)8-6-7-9-17(4)32-25(31)18(5)23(29)26(27,28)24(30)22(20)21/h6-12,15-22H,13H2,1-5H3/b8-6-,9-7+/t15-,16-,17+,18+,19-,20+,21-,22-/m1/s1 |
| SMILES | C[C@@H]1/C=C\C=C\[C@@H](OC(=O)[C@H](C(=O)C(C(=O)[C@@H]2[C@H]1C=C[C@H]3[C@H]2[C@@H](C=C(C3)C)C)(Cl)Cl)C)C |
ORIGINAL ISOLATION REFERENCE
| CITATION | Held, Jana; Gebru, Tamirat; Kalesse, Markus; Jansen, Rolf; Gerth, Klaus; Müller, Rolf; Mordmüller, Benjamin Antimalarial activity of the myxobacterial macrolide chlorotonil a Antimicrobial Agents and Chemotherapy 2014 58 (11) 6378-6384. | ||
|---|---|---|---|
| DOI | 10.1128/aac.03326-14 | PMID | 25114138 |
SYNTHESES
| CITATION 1 | Rahn N; Kalesse M The total synthesis of chlorotonil A. Angewandte Chemie International Edition 2008 47 (3) 597-599. DOI: 10.1002/anie.200703930 PMID: 18041801 | ||
|---|---|---|---|
