Loading...

Loading...

Compounds

COMPOUND NPA004854

STRUCTURE
Image structure
EXPORT OPTIONS PNG JSON SDF
PROJECT MOLECULE TO GLOBAL VIEW See Global
EXTERNAL LINKS
mibig logo npmrd logo unichem logo
PROPERTIES
NPAID NPA004854
CLUSTER ID 95
NODE ID 90
NAME Sesquicillin
FORMULA C29H42O5
MOLECULAR WEIGHT (Da) 470.6500
ACCURATE MASS (Da) 470.3032
ORIGIN ORGANISM TYPE Fungus
ORIGIN GENUS Albophoma
ORIGIN SPECIES sp. FKI-1778
InChIKey XYRWDMXUDDAXMF-JJPZVYOZSA-N
InChI InChI=1S/C29H42O5/c1-17(2)10-9-14-29(8)24-12-11-18(3)23(28(24,7)15-13-25(29)34-21(6)30)16-22-26(31)19(4)20(5)33-27(22)32/h10,23-25,31H,3,9,11-16H2,1-2,4-8H3/t23-,24-,25+,28-,29+/m1/s1
SMILES CC1=C(OC(=O)C(=C1O)C[C@@H]2C(=C)CC[C@@H]3[C@@]2(CC[C@@H]([C@@]3(C)CCC=C(C)C)OC(=O)C)C)C
ORIGINAL ISOLATION REFERENCE
CITATION Engel, L; Erkel, G; Anke, T; Sterner, O Sesquicillin, an inhibitor of glucocorticoid mediated signal transduction Journal of Antibiotics 1998 51 (5) 518-521.
DOI 10.7164/antibiotics.51.518 PMID 9666183
ORIGINAL ISOLATION TAXONOMY
RANK NAME DB LINK NCBI
Domain Eukarya - 2759
Kingdom Fungi MycoBank 4751
Phylum Ascomycota MycoBank 4890
Genus Albophoma MycoBank 1635094
SYNTHESES
CITATION 1 Zhang F; Danishefsky SJ An efficient stereoselective total synthesis of DL-sesquicillin, a glucocorticoid antagonist. Angewandte Chemie International Edition 2002 41 (8) 1434-7. DOI: 10.1002/1521-3773(20020415)41:8<1434::aid-anie1434>3.0.co;2-a PMID: 19750790
CLASSYFIRE
Show Hide
NP CLASSIFIER
Show Hide