Compounds
| ID | Spectrum Quality | Annotated Name |
|---|
COMPOUND NPA003055
PROPERTIES
| NPAID | NPA003055 |
|---|---|
| CLUSTER ID | 1742 |
| NODE ID | 543 |
| NAME | Nobilamide B |
| FORMULA | C43H61N7O10 |
| MOLECULAR WEIGHT (Da) | 836.0000 |
| ACCURATE MASS (Da) | 835.4480 |
| ORIGIN ORGANISM TYPE | Bacterium |
| ORIGIN GENUS | Streptomyces |
| ORIGIN SPECIES | sp. CN48 |
| InChIKey | BIFGNCSVWQWVNT-JCEJUIOTSA-N |
| InChI | InChI=1S/C43H61N7O10/c1-9-30(43(59)60)46-37(53)26(7)44-41(57)35(25(5)6)49-42(58)36(27(8)51)50-40(56)33(23-29-19-15-12-16-20-29)48-38(54)31(21-24(3)4)47-39(55)32(45-34(52)10-2)22-28-17-13-11-14-18-28/h9,11-20,24-27,31-33,35-36,51H,10,21-23H2,1-8H3,(H,44,57)(H,45,52)(H,46,53)(H,47,55)(H,48,54)(H,49,58)(H,50,56)(H,59,60)/b30-9-/t26-,27+,31+,32-,33-,35-,36+/m0/s1 |
| SMILES | CCC(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@H](CC(C)C)C(=O)N[C@@H](CC2=CC=CC=C2)C(=O)N[C@H]([C@@H](C)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C)C(=O)N/C(=C\C)/C(=O)O |
ORIGINAL ISOLATION REFERENCE
| CITATION | Lin, Zhenjian; Reilly, Christopher A.; Antemano, Rowena; Hughen, Ronald W.; Marett, Lenny; Concepcion, Gisela P.; Haygood, Margo G.; Olivera, Baldomero M.; Light, Alan; Schmidt, Eric W. Nobilamides A-H, Long-Acting Transient Receptor Potential Vanilloid-1 (TRPV1) Antagonists from Mollusk-Associated Bacteria Journal of Medicinal Chemistry 2011 54 (11) 3746-3755. | ||
|---|---|---|---|
| DOI | 10.1021/jm101621u | PMID | 21524089 |
SYNTHESES
| CITATION 1 | Jacinto MP; Flores MS; Lin Z; Concepcion GP; Schmidt EW; Faulkner S; Villaraza AJ Synthesis and bioactivity of nobilamide B. RSC Advances 2014 4 (71) 37609-37612. DOI: 10.1039/C4RA06873D PMID: 26167276 | ||
|---|---|---|---|
